ANTIOXIDANT AND ANTI-CANCER IN VITRO EFFECT CURCULIGO ORCHIOIDES IN SON DUONG DISTRICT, TUYEN QUANG PROVINCE.
DOI:
https://doi.org/10.51453/2354-1431/2022/760Keywords:
Curculigo orchioides, Son Duong, Tuyen QuangAbstract
Curculigo orchioides Gaertn. (Hypoxidaceae) is a perennial herb with long cylindrical rhizomes. The rhizomes of this plant possess various medicinal as well as other properties such as cooling, diuretic, aphrodisiac, tonic hemorrhoids, leucorrhoea, pruritis, skin diseases, asthma, bronchitis, jaundice, cancer, diarthrosis wound healing etc … Antioxidant activity by DPPH assay, The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay is used to measure cellular metabolic activity as an indicator of cell viability, proliferation and cytotoxicity the results showed that: The extract SC.E, SC, SCM exhibit antioxidant activity at SC50 38,05 µg/ml, 48,03 µg/ml, 94,04 µg/ml. The extract SC, SC.E showing the strongest activity against liver cancer cell line Hep-G2 at IC50 37,2 μg/ml và 18,9 μg/ml. The remaining samples had weak or no activity.
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