ANTIOXIDANT AND ANTI-CANCER IN VITRO EFFECT CURCULIGO ORCHIOIDES IN SON DUONG DISTRICT, TUYEN QUANG PROVINCE.

Authors

  • Tran Duc Dai Tan Trao University
  • Do Cong Ba Tan Trao University, Vietnam
  • Tong Van Truong Tan Trao University, Vietnam
  • Nguyen Thi Nguyet Tan Trao University, Vietnam
  • Ngo Thanh Huyen Tan Trao University, Vietnam
  • Duong Thị Diem Quynh Tan Trao University, Vietnam
  • Tran Thanh Hoai Tan Trao University, Vietnam
  • Luong Thi Thuy Duong Tan Trao University, Vietnam
  • Mena Phathongin Tan Trao University, Vietnam

DOI:

https://doi.org/10.51453/2354-1431/2022/760

Keywords:

Curculigo orchioides, Son Duong, Tuyen Quang

Abstract

Curculigo orchioides Gaertn. (Hypoxidaceae) is a perennial herb with long cylindrical rhizomes. The rhizomes of this plant possess various medicinal as well as other properties such as cooling, diuretic, aphrodisiac, tonic hemorrhoids, leucorrhoea, pruritis, skin diseases, asthma, bronchitis, jaundice, cancer, diarthrosis wound healing etc … Antioxidant activity by DPPH assay, The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay is used to measure cellular metabolic activity as an indicator of cell viability, proliferation and cytotoxicity the results showed that: The extract SC.E, SC, SCM exhibit antioxidant activity at SC50 38,05 µg/ml, 48,03 µg/ml, 94,04 µg/ml. The extract SC, SC.E showing the strongest activity against liver cancer cell line Hep-G2 at IC50 37,2 μg/ml và  18,9 μg/ml. The remaining samples had weak or no activity.

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Published

2022-07-12

How to Cite

Trần Đức, Đại, Đỗ Công, B., Tống Văn, T., Nguyễn Thị, N., Ngô Thanh, H., Dương Thị Diễm, Q., Trần Thanh, H., Lương Thị Thùy, D., & Phathongin, M. (2022). ANTIOXIDANT AND ANTI-CANCER IN VITRO EFFECT CURCULIGO ORCHIOIDES IN SON DUONG DISTRICT, TUYEN QUANG PROVINCE. SCIENTIFIC JOURNAL OF TAN TRAO UNIVERSITY, 8(2). https://doi.org/10.51453/2354-1431/2022/760

Issue

Section

Natural Science and Technology